EFFICACY AND SAFETY OF TREATMENT REGIMENS FOR PATIENTS WITH METASTATIC, LOCALLY ADVANCED, OR RECURRENT BREAST CANCER CARRYING BRCA1/BRCA2 PATHOGENIC VARIANTS: A NETWORK META-ANALYSIS

ObjectivePatients with breast cancer carrying BRCA1 and BRCA2 genetic alterations show poor prognoses.However, the efficacy of pharmacotherapies for patients with advanced breast cancer carrying BRCA1/2 pathogenic variants remains unclear.This study aimed to conduct a network meta-analysis to assess the efficacy and safety of various pharmacotherap

In this study, a novel silver solution was prepared by a simple green synthesis method using AgNO3, neem and salep extracts at room temperature.The results of UV-Visible spectrophotometer CHO-LES-TERIN and Scanning Electron Microscopy (SEM) showed the formation of silver particles with a star-like morphology and sharp edges in the solution.In order

An age-related distribution of Cryptosporidium species has been reported in cattle, with C.parvum being predominant in suckling calves, C.bovis and C.ryanae being predominant in post-weaned calves and C.andersoni being predominant in adults.However, variants to this pattern have recently been reported.Thus, fecal samples (n = 594) from asymptomatic

Biomimetics must be taught to the next generation of designers in the interest of delivering solutions for current problems.Teaching biomimetics involves teachers and students from and in various disciplines at Miele KMDA 7633 FL Induction Hob With Integrated Extractor different stages of the educational system.There is no common understanding of h

Background: Carthamus tinctorius L., known as Kafesheh (Persian) and safflower (English) is vastly utilized in Traditional Medicine for various medical conditions, namely dysmenorrhea, amenorrhea, postpartum abdominal pain and mass, trauma and pain of joints.It is largely used for flavoring and coloring purposes among the local population.Recent re